Kiehl's best face cream uniquely formulated for all skin types. Made in USA. Provides lasting 24-hour hydration for soft, smooth, healthy-looking skin. Balances skin’s driest areas with 2.3X more moisture. Apply to cleansed and toned facial skin day or night as needed, avoiding the immediate eye area. Explore Ultra Facial Collection. Antarcticine (Glacial Glycoprotein Extract) Antarcticine, sourced from Antarctica, is a glycoprotein* that has demonstrated many unique benefits when used in skincare formulas. With superb protection against dryness, Antarcticine helps hydrate skin and provides it with a noticeably smoother appearance while shielding skin from the damaging effects of free-radicals. It further helps to protect skin from extremely cold temperatures, facilitating skin’s retention of natural water reserves. The organic substance thrives in the most extreme environmental conditions as a result of the cryoprotective (protection against freezing) properties of the molecule.* A glycoprotein is a macromolecule composed of a protein and a carbohydrate (an oligosaccharide). Squalane (Perhydrosqualene or perhydrosqualene vegetal) A signature Kiehl’s ingredient, Squalane is a botanical lipid that is similar in molecular structure to natural skin lipids. It has an exceptional affinity to skin, and because it’s easily absorbed, Squalane helps restore skin’s natural moisture balance to keep it extra soft and supple.