The possible impacts of global climate change on different countries has led to the development and ratification of the Framework Convention on Climate Change (FCCC) and has a strong bearing on the future sustainable development of developing countries and countries with economies in transition. The preparation of analytical methodologies and tools for carrying out assessments of vulnerability and adaptation to climate change is therefore of prime importance to these countries. Such assessments are needed to both fulfill the reporting requirements of the countries under the FCCC as well as to prepare their own climate change adaptation and mitigation plans. The vulnerability and adaptation assessment guidelines prepared by the U.S. Country Studies Program bring together all the latest knowledge and experience from around the world on both vulnerability analysis as well as adaptation methodologies. It is currently being applied successfully by scientists in over fifty countries from all the regions of the globe. This guidance is being published to share it with the wider scientific community interested in global climate change issues. This guidance document has two primary purposes: - To assist countries in making decisions about the scope and methods for their vulnerability and adaptation assessments, - To provide countries with guidance and step-by-step instructions on each of the basic elements of vulnerability and adaptation assessments.