The Danish aristocrat and astronomer Tycho Brahe personified the inventive vitality of Renaissance life in the sixteenth century. Brahe lost his nose in a student duel, wrote Latin poetry, and built one of the most astonishing villas of the late Renaissance, while virtually inventing team research and establishing the fundamental rules of empirical science. His observatory at Uraniborg functioned as a satellite to Hamlet’s castle of Kronborg until Tycho abandoned it to end his days at the court of the Holy Roman Emperor Rudolf II in Prague. This illustrated biography presents a new and dynamic view of Tycho’s life, reassessing his gradual separation of astrology from astronomy and his key relationships with Johannes Kepler, his sister Sophie, and his kinsmen at the court of King Frederick II.