This volume explores the intricate relationships that the universe of Frank Herbert's Dune portrays between faith, prophecy, and spirituality. The Dune universe is a large and complex place where social, political, and cultural structures are intricately interwoven with religious, theological, and philosophical ideas. From the syncretism of the Ecumenical Translation Project and the Orange Catholic Bible, through to the messianic aspirations of the Bene Gesserit, and the subsequent transhumanism of Leto II as the God-Emperor. Through, the desert planet Arrakis-the series' epicentre-is portrayed as a location where fate and faith collide. It is also a place where the vital function of religious and theological motifs may be examined as they influence the plot and character development throughout the series. The essays in this volume dance throughout the breadth of Frank Herbert's Dune universe, along with some also considering Brian Herbert and Kevin Anderson's Legends of Dune trilogy. They examine the complex ways in which religious and theological constructs shape and are shaped by the characters and the evolving landscape of the Dune universe, and in the mind of the reader.