The Ladies of D-block are back in part 3 of the saga. The departure of Dre causes a power struggle for control of the prison's lucrative market. The new warden has her hands full trying to keep track of all the players. Especially when new players join the game. Prentiss still struggles to come to grips with her new reality. She's prey in a comcrete and steel jungle full of predators. All looking to feed on the new meat. Amanda is biding her time until her next court date. Newly discovered evidence could set her free, but the Sisterhood's newly discovered evidence could cost her life. Lisa has a new hustle but it comes at a cost. Stepping on toes is dangerous anywhere but can be deadly in D-block. Officer Chuck Stanton is still learning the ropes and trying to follow the rules. The lines blur when he finds himself drawing closer to a particular inmate. Meanwhile, his partner Daryl Johnson may very well have lost his mind. The City Girls, Gangster Girls, Sisterhood, Snowflakes and the Mexicans are all vying to reach the top of the food chain. While the Muslimahs close their ranks and try to stray above the fray. The Ladies of D-block 3, starts now.