The House Behind the Cedars story occurs in the southern American states of North and South Carolina a few years following the American Civil War. Rena Walden, a young woman of mixed white and black ancestry, leaves home to join her brother, who has migrated to a new city, where he lives as a white man. Following her brother's lead, Rena begins living as a white woman. The secret of her identity leads to conflict when she falls in love with a white aristocrat who learns the truth of her heredity.