Four bright teenage girls from St. George's, an international school in Rome, put their lives on the line to save a baby rhino from a bankrupt Italian zoo. The girls are inspired by a class visit from a local zookeeper who shares her experience as an African game warden. Their plan is set in motion when they discover the new zoo director is a poacher. Each girl is powerful, and they use their unique talents, ingenuity, and diverse friendship to outfox the director's evil intentions. The catacombs will awaken as the girls utilize ancient Roman ruins and the city's streets as their battleground, turning the story of St. George upside down to save a rhino.