IMPORTANT: the format of this ebook is EPUB3 FIXED LAYOUT. You can read it ONLY on: APPLE IPAD and MAC with iBooks (LATEST VERSIONS - http://bit.ly/download_ibooks); GOOGLE CHROME with READIUM web app (online and offline reading on pc). You have to install first GOOGLE CHROME (DOWNLOAD: http://www.google.com/intl/us/chrome/browser/) and then READIUM (http://bit.ly/download_readium), adding it as an EXTENSION OF CHROME. After purchasing, click on the download button and open the file with iBooks; to add the ebook to Readium, click on the plus icon in the navigation bar and select the file on your pc/tablet (video tutorial). As you download it, you accept all terms and conditions that you can find at www.francoangeli.it. This ebook is licensed for your personal use only. You are not authorized to share, sell, reproduce or distribute it or parts of it to others. It includes interactive widgets, audio and video files that will enrich your reading and learning experience. THE FILE SIZE IS ABOUT 130 MB, SO WE RECOMMEND USING A BROADBAND CONNECTION FOR DOWNLOADING. FOR HELP AND SUPPORT: ANGELO VENTRIGLIA - ventriglia@francoangeli.it The recently released autocontouring and advanced imaging software are rapidly gaining growing attention in the contemporary scientific landscape. Their aim is to lower the contouring time burden, allowing in the meanwhile a more accurate adherence to the existing guidelines and strongly reducing the interobserver variability which still represents a major source of error in Radiotherapy. But besides these promising benefits, the user must be aware that these software still present technical and ontological limits that could decrease their clinical reliability. Aim of this ebook is to present the existing state of art, to support those who intend to report their experiences with autocontouring software and to describe the principal aspects and variables that must be considered and analyzed when setting up a research study directed to efficaciously evaluate these software. The different aspects of this fascinating topic will be highlighted in specific units of knowledge, where the text is enriched by figures, tables and fully interactive widgets that assure a faster and easier learning.