Polycystic Ovary Syndrome (PCOS) is a hormonal disorder common among women of reproductive age. It is characterized by enlarged ovaries containing multiple small cysts, which often lead to irregular menstrual cycles and difficulties in conceiving. PCOS can also cause symptoms such as excess hair growth, acne, and weight gain. While the exact cause is unknown, genetics and insulin resistance are believed to play significant roles. Managing PCOS involves a combination of lifestyle changes, such as maintaining a healthy diet and regular exercise, along with medical interventions like hormonal birth control to regulate menstruation and fertility treatments for those trying to conceive. Early diagnosis and treatment are crucial to mitigate potential complications like infertility, type 2 diabetes, and cardiovascular disease associated with PCOS. Consulting a healthcare provider for personalized guidance is essential for women dealing with PCOS. This book attempts to understand the basic science behind Polycystic Ovary Syndrome and the recent clinical advances. Most of the topics introduced in this book cover novel research in this field. As this field is emerging at a fast pace, this book will help the readers to better understand the concepts of female reproductive health.