Neem or Azadirachta indica is the multifaceted medicinal plant species which is most widely distributed in sub-continental area including many states of India, Pakistan, and Sri Lanka etc. But due to its immense medicinal and economical potential, it has transferred to both tropical and subtropical zones where they start the cultivation of Neem. Neem tree possesses some majestic properties and are considered as rich source of limonoids, some essential amino acids, and several fatty acids. Moreover, Neem tree is considered as the heaven tree due to its enormous beneficial aspects including its products such as Neem oil used as for various medicinal purposes, Neem cake, and Neem seed kernel extract have extensive application in agriculture or agro-forestry.