Fans of Anne Tyler's quirky characters and her attention to family life, or Pete Hamill's depiction of diverse, ethnic, urban neighborhoods will connect to Most Precious Blood, set in the eleventh-hour of a declining Italian-American neighborhood where complex and often destructive loyalties have dire consequences. Hard Luck Lenny is the quintessential good son, brother, and father, and he fears a calamity will derail his son's future the way his own dreams were derailed years ago, but Frankie is preoccupied with thoughts of Gennaro DiCico, the son of a small-time mobster. Lenny's fears are realized when a cabdriver's son avenges his father's murder.