Mobilization and stimulation of neuromuscular tissue (MaSoNT) is a "hands-on" treatment technique which is applied in neurorehabilitation and aims to enhance and facilitate muscle activity. At MaSoNT, the therapist applies several maneuvers in order to bring nerve and muscle fibers into contact as this elicits recovery responses for stroke patients in terms of both facilitation and inhibition. In this course, details with regards to physiology is given at the first part. There, some analysis is provided on physiology of how the generated signal is triggered and travels all the way to the higher centers of the central nervous system in healthy individuals. Moreover, there is some emphasis on how stroke changes it all and then focus on what is the physiological response on the "bottom-up" somatosensory techniques we therapists apply in every-day clinical practice. To that end, you will find interesting to learn how motor learning works and offers the principles upon which us therapists choose to guide the procedures of cortical reorganization inside stroke patient's brain towards functional recovery. To sum up, in this part you will learn why we use MaSoNT in stroke recovery.