This book presents a collection of high-quality, peer-reviewed research papers from the 6th International Conference on Information System Design and Intelligent Applications (INDIA 2019), held at Lendi Institute of Engineering & Technology, India, from 1 to 2 November 2019. It covers a wide range of topics in computer science and information technology, including data mining and data warehousing, high-performance computing, parallel and distributed computing, computational intelligence, soft computing, big data, cloud computing, grid computing and cognitive computing.