This two-volume set LNCS 16169&16170 constitutes the refereed proceedings of the 23rd International Conference on Image Analysis and Processing, ICIAP 2025 Workshops, held in Rome, Italy, during September 15&19, 2025.The 105 papers included in these proceedings were carefully reviewed and selected from 348 submissions. The papers are organized in the following topical sections:Volume I:4th Automatic Affect Analysis and Synthesis Workshop (3AS 2025); International Workshop on Advances in Drone Vision (ADV 2025); 3rd International Workshop on Artificial Intelligence and Radiomics in Computer-Aided Diagnosis (AIRCAD 2025); 2nd International Workshop on Computer Vision for Environment Monitoring and Preservation (CVEMP 2025); Workshop on Computer Vision and Generative Models for Medical Imaging (CVGMMI 2025); Human-Object Interaction: Integrating Egocentric and Exocentric Perspectives (HOI-EGO-EXO 2025); 4th International Workshop on Fine Art Pattern Extraction and Recognition (FAPER 2025); 2nd Workshop on Generation of Human Face and Body Behavior (GHB 2025); and 1st International Workshop on Humans in the eXtended Artificial Intelligence Loop (HUARL 2025).Volume II:1st Workshop on Innovative Medical image Processing with AI-driven preCision Technologies (IMPACT 2025); INSAIT: INterpretable Systems for Artificial Intelligence Transparency (INSAIT 2025); 1st Workshop on Advances in Modular Deep Learning; Neuro-Inspired AI; 5th International Workshop on Pattern Recognition for Cultural Heritage (PatReCH 2025); Reliable AI and Uncertainty Quantification in Image Analysis (RelAI 2025); 4th International Workshop on Traffic and Street Surveillance for Safety and Security (IWT4S 2025); 2nd Workshop on Trustworthy Generative AI for Image and Video Synthesis: Challenges, Ethics, and Applications (TRUEGEN-VIS 2025); 2nd International Workshop on Video Surveillance Systems in Smart Cities: Synthetic Images and Foundation Models for Advanced Monitoring Technologies (V3SC 2025); 4th International Workshop on Recent Advances in Digital Security: Biometrics and Forensics (BioFor 2025); 1st International Workshop on Imaging, AI, VR and AR in Food Research to Enhancing Safety, Quality and Consumer Insights (ImagEAT 2025); Alternative Visual Domains for Detection, Tracking and Forecasting (AVD 2025); Dual Factor Lip-Based Biometric User Authentication; 2nd International Contest on Real-Time Fire Detection on the Edge (ONFIRE 2025); and OCT-Cyst Challenge: A Competition for Cyst Segmentation in Optical Coherence Tomography Images (OCT-Cyst Challenge 2025).