History of Rabies in the Americas, Volume III: Reflections, Reports, Retrospectives, and Revelations is a natural outgrowth of the prior two volumes, which presented topical and spatio-temporal insights on this theme. Volume III offers contributions from those with first-hand experiences with this disease, from groundbreaking discoveries in control and prevention, to the first person to survive rabies without prior vaccination. This volume goes beyond the objectivity of science writing to offer personal narratives detailing individual impacts, the local and global contributions authors have made to detection, prevention, and control, and the long-reaching effects of colonization and disease translocation into this region. The introduction of rabies to the Americas occurred much later than the rest of the world, and the region has played a uniquely pivotal role in global understanding of this disease. Rather than rehashing the topics presented in the first two volumes, Volume III focuses on the leadership role the Americas has played, in the words of those who experienced it first-hand.