The first part of this compilation contains articles that highlight the main challenges to the structure of global governance, trade, and development. They are based on empirical analysis resulting from my own professional experience with both the United Nations? system and trade negotiations. They show the challenges that multilateral regimes face in maintaining their relevance. The second part of this compilation contains reflections on how the financial crisis has affected Europe and, what I believe, are the links with educational systems that have not been adapted to the new realities of the globalized world economy. Europe is stuck in fear and, therefore, does not manage to mobilize its creative potential to develop innovative solutions for youth and entrepreneurs. It looks at ?what it used to be? rather than at ?what it is to be? in the future. Education and training methodologies must be adapted to the new economic realities to encourage young people to think creatively and innovate.