I am also seriously wondering why I am writing this book on this subject, but what should I say? I also had my first love, and it compelled me to write this book. Love is a natural phenomenon associated with human life. We can't get freedom from love. I think God also can't escape from this. We can say there is a strong relationship between males and females in human life. Scientifically, the particular male and female child so attracted to each other with their closed minds that they do not want to be separated from their entire lives is called the first love. Keeping scientific thoughts in mind, I also ignored my first love and took it lightly because I wanted to get a doctorate before my death. For that, I studied my entire life, and finally, I got it. But somewhere in my heart was clicking the pains of my first love, and I forcefully agreed that to date I couldn't escape from my first love, and I think it was impossible for me. Because of this happening to me, I am quite surprised at what is true and wrong in my life. Now this question has been arising seriously in my life. Being a science student, I know the function of the human brain, and my brain functions under no control; it automatically tunes up with my first love. So, I suggested to people: please don't take it lightly; otherwise, you will suffer from your first love. And request that society and the government please take care of the physical and financial help of their young children from this first-love depression; otherwise, their lives will be meaningless, and this will become the only cause of depression in their lives without any proper reason, so we have to take the utmost care in this regard. Please follow the guidelines mentioned in this book to be saved from the depression of first love. Hence this handbook.