This book delves into antibiotic resistance, offering insights into its emergence, mechanisms, and impact on global health. The book also scrutinizes over-prescription, agricultural use, and the scarcity of new drug development, while spotlighting the role of globalization in its propagation. It moves beyond conventional approaches, examining alternative strategies like phage therapy, immunotherapy, and nanotechnology. Highlighting precision diagnostics and the importance of policy implications, it navigates through public health strategies, surveillance, and international collaborations. Finally, it glimpses into the future, delineating the challenges, opportunities, and the urgency of action required to steer away from a post-antibiotic era. This book serves as an invaluable resource for students, researchers, and scientists in the fields of medicine, pharmacy, microbiology, and public health.