This book constitutes the refereed proceedings of the 24th International Conference on Distributed Applications and Interoperable Systems, DAIS 2024, held in PhGroningen, The Netherlands, as Part of the 19th International Federated Conference on Distributed Computing Techniques, DisCoTec 2024, during June 17-21, 2024. The 5 full papers included in this book were carefully reviewed and selected from 17 submissions. They focus on all practical and conceptual aspects of distributed applications, including their design, modeling, implementation, and operation; the supporting middleware; appropriate software engineering methodologies and tools; and experimental studies and applications.