As first-generation students gain greater access to higher education, faculty, and staff at colleges and universities must provide intentional engagement that supports their persistence and graduation. This book serves as a guidebook for higher education practitioners seeking to implement or enhance first-generation programming at their institutions. The chapters provide detailed descriptions of the development, implementation, and assessment of programs and practices intended to support the success of first-generation college students. Authors share insights on building allies, identifying and working through challenges, and applicable takeaways for implementing similar practices and programs at the reader's own institutions. Programming discussed in the book ranges in funding levels and includes activities such as faculty dinners, study abroad, bridge programs, living learning communities, peer mentoring, intrusive advising, and holistic well-being. This valuable resource helps higher education practitioners better support and position first-generation students for success.