This book constitutes the refereed proceedings of the 29th Argentine Congress of Computer Science on Computer Science - CACIC 2023, held in Luján, Argentina, during October 9-12, 2023.  The 27 full papers included in this book were carefully reviewed and selected from 142 submissions. They were organized in topical sections as follows: agents and systems; distributed and parallel processing; technology applied to education; graphic computation, images and visualization; software engineering; databases and data mining; hardware architectures, networks, and operating systems; innovation in software systems; signal processing and real-time systems; innovation in computer science education; computer security; digital governance and smart cities.