This book constitutes the proceedings of the 24th International Workshop on Computer Algebra in Scientific Computing, CASC 2022, which took place in Gebze, Turkey, in August 2022.  The 20 full papers included in this book were carefully reviewed and selected from 32 submissions. They focus on the theory of symbolic computation and its implementation in computer algebra systems as well as all other areas of scientific computing with regard to their benefit from or use of computer algebra methods and software.