Regenerative medicine is a field of medicine that develops methods to create, repair or replace diseased or harmed cells, tissues or organs. This discipline encompasses the development and application of therapeutic stem cells, the creation of artificial organs, as well as tissue engineering. The heart holds a limited ability of self-renewal and this limitation can be overcome with the usage of nanotechnologies and nanomaterials in cardiovascular tissue engineering. Cardiac regeneration uses cutting-edge research, such as cell-free and stem cell therapy to heal damaged heart tissue. Tools for repair have been developed to use the body's inherent capacity for regeneration to restore damaged cardiac tissue and function. Cardiac stem cell therapy has the potential to stimulate myocardial regeneration in patients suffering from ischemic heart disease. This book explores all the important aspects of cardiovascular regenerative medicine. It includes some of the vital pieces of work being conducted across the world, on various topics related to the use of nanotechnology as well as the clinical applications of this field. This book will provide comprehensive knowledge to the readers.