Boorman and Leininger&s Pathology of the Rat: Reference and Atlas, Third Edition offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, it provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. This is the most comprehensive publication on rat pathology, making it an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology. With updated references and photographs, as well as coverage of all rat strains, this book is the standard in the field for professionals who must make the transition from pathology results to the promulgation of meaningful regulations. Uses photomicrographs from the NTP archive, other archives, and resources to make the photomicrograph atlas aspect of the book as extensive as possible Updates and expands on previous chapters Evaluates tumor findings to assist readers in interpreting tumor data (including statistical analysis) and determining whether test compounds should be regarded as carcinogenic or otherwise Includes examples of tumor profiles obtained from NTP studies and pharmaceuticals evaluated by the FDA