This book is the comprehensive collection of research-based data from the studies on coastal ecosystems of Malaysia (especially from the east coast of peninsular Malaysia). The book consists of nine chapters addressing the issues related to (but not limited to) the bio-prospect potential such as screening of actinomycetes from the coastal ecosystem, microbial bioprospecting using 'omics' approach, importance of integrated Multi-trophic Aquaculture, biotic diversity and shoreline erosion in coastal ecosystem. We are optimistic to say that the in-depth knowledge and scientific insights shared in this book will contribute towards sustainable development goals holistically and in particular on SDG 13,14 and 15.