In this issue of Clinics in Liver Disease , guest editor Dr. David E. Bernstein brings his considerable expertise to the topic of Autoimmune Hepatitis Including PBC and PSC . The three main immune disorders that involve the liver are AIH, primary biliary cholangitis, and primary sclerosing cholangitis. As these autoimmune diseases can share symptoms, it is important for the hepatologist to have clinical knowledge of each and understand their differences and similarities. This issue addresses these variants and provides the reader with important information relating to pathology, diagnosis, and treatment.