This book aims to create a cohesive and logically structured scientific concept, a systemic methodology, and a set of practical recommendations for the human-centered use of artificial intelligence (AI) in socio-economic systems. In its five parts, the book explains the role and place of the individual in smart socio-economic systems, presenting advanced human-centered solutions for the use of AI in the economy, which spans various industries, regions, and countries. The book is notable for its multidisciplinary approach, offering a systemic perspective on human-centered AI applications from the standpoint of various social sciences, including economics and management, law, sociology, philosophy, cultural studies, pedagogy, and psychology. The novelty of this book lies in its consideration of the empirical experience of humanizing cyber-social systems in developed and emerging smart economies, including the dynamically developing EAEU and Central Asian countries. The primary audience for the book consists of scholars studying AI. In this book, they will find a socio-humanitarian view of the AI economy and a comprehensive scientific methodology for its humanization. Additionally, the book is of interest to representatives of smart enterprises, leaders of smart regions, and government officials in countries implementing artificial intelligence who are concerned with issues related to its humanization.