This book constitutes the proceedings of the 7th International Conference on Algorithms and Discrete Applied Mathematics, CALDAM 2021, which was held in Rupnagar, India, during February 11-13, 2021.  The 39 papers presented in this volume were carefully reviewed and selected from 82 submissions. The papers were organized in topical sections named: approximation algorithms; parameterized algorithms; computational geometry; graph theory; combinatorics and algorithms; graph algorithms; and computational complexity.