After encountering and destroying roving bands of werewolves as boys along the Mississippi River, in Ohio and Maryland, Huck leaves his friends and embarks on a journey to find the reason for strange new feelings that have overwhelmed him. After he returns to school in Maryland, Huck, along with Tom and Jim begin their new travels through life, which turn out to be anything other than ordinary. Jim settles in with his family hundreds of miles away as Huck and Tom join the Army at West Point and take their battles with lycanthropes through Mexico, the Civil War and beyond. As he ages, Huck begins to discover things about his past that he never imagined, and finds new mysteries that beg to be solved. Set against the background of a fairly young and ever expanding United States, Huck meets, interacts with and befriends many of the famous Americans of his time.