This book constitutes the proceedings of the 17th International Conference on Practical Applications of Agents and Multi-Agent Systems, PAAMS 2019, held in Ávila, Spain, in June 2019. The 19 regular and 14 demo papers presented in this volume were carefully reviewed and selected from 55 submissions. They deal with the application and validation of agent-based models, methods, and technologies in a number of key applications areas, including: Agronomy and Internet of Things, coordination and structure, finance and energy, function and autonomy, humans and societies, reasoning and optimization, traffic and routing.