Advances in Clinical Chemistry, Volume 127explores physiologic and pathophysiologic biochemistry in both general and clinical chemistry. Complex molecular pathways are elucidated using historical, current, and emerging technologies such as biosensor design, metabolomics, and proteomics. Chapters in this new release include The Cancer Microbiome, Metabolomics of Nephrotic Syndrome, Advances in Biomimetic Sensor Technology, Gel electrophoresis-based proteoform separation and analysis, Advances in blood microsampling technology for cancer biomarker detection, and MDDB: A public databank of host microRNAs in Tuberculosis diagnosis. Presents the latest information on the microbiome in carcinogenesis Includes discussions on metabolomics and proteomics Provides updates on biosensor design and microsampling in clinical laboratory diagnosis and TDM