This book constitutes the refereed proceedings of the Second International Conference on Advanced Communication and Intelligent Systems, ICACIS 2023, held in Warsaw, Poland, during June 16-17, 2023 The 43 full papers included in this book were carefully reviewed and selected from 221 submissions. They were organized in topical sections as follows: Wireless Communication, Artificial Intelligence and Machine Learning, Robotics & Automation, Data Science, IoT and Smart Applications