40 Something is a window of a few weeks in the life of twelve friends, their relationships, their fears, their idiosyncrasies and their dreams. The fiction is set in contemporary Melbourne's Port Phillip Bay , following the twelve main characters and their friendship in what has become a rather peculiar, close family. Starring around the big table Luca , the devoted photographer, veteran of two divorces, often suspended between wisdom and confusion. Patricia , the idealistic, inspired actress mostly out of work, but passionately free from compromises. Manuel and Allison , the odd couple run out of breath preparing for the last leg of their journey, stuck in a battle of coercion and control. Michael and Josie , the two survivors in search of new possibilities, lost in an ocean of boredom and disillusion. Jonas and Silvie , the couple close to be stepping into the zone of no return in their relationship, protagonists of a story built on thin poles and just about to crumble. Ross and Kathy , the successful couple structured and carefully assembled piece-by-piece, who have planned their life together, at each step, with no room for the "unexpected". Liam , the happy gigolo by birth and single by definition, cruising through life, like a speeding luxury yacht. Pamela , the attractive blond, once female essence lost in drug addiction; a living miracle, suddenly propelled to stardom. Cat , the single mother finally feeling like a woman again after her divorce